Our veterinary surgeons are recognised national and international experts. In addition to providing specialist clinical services we carry out research to advance our understanding of animal diseases, enabling us to further help our patients, other animals and even humans. Where Research Meets Clinical Care Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective. Clinical trials are the best way to study new treatments because the disease has occurred spontaneously in your pet, rather than being imposed within an artificial laboratory environment. Clinical studies follow strict scientific standards. These standards protect patients and help produce reliable study results. Clinical trials start with small groups of patients to find out whether a new approach will be beneficial and well tolerated. In later phases of clinical trials, researchers learn more about the new approach's risks and benefits by treating larger numbers of pets. These studies also may show which medical approaches work best for certain illnesses or groups of subjects. Clinical trials often produce the best data available for veterinary care decision-making. Novel oral medication for dogs with lymphoma Rimcazole is a new anti-cancer medicine that we are investigating in dogs wth lymphoma. Rimcazole has shown anti-cancer effects in two ways: by stimulating cancer cells to self-destruct and by preventing the formation of new blood vessels. Both of these mechanisms should inhibit tumour growth. Immunotherapy for dogs with melanoma P28R is a new anti-cancer drug that we are investigating in dogs with melanoma. P28R works by helping the bodies own immune system to fight cancer cells. P28R has been tried in pilot studies but we now want to see if it can help our patients. Topical bleosome to treat skin tumours in canine patients Bleosome is a novel chemotherapy topical drug formulation aimed at the treatment of some kinds of skin tumours. Bleosome works by binding to the cancer cells' DNA so that the cells can't divide or grow. It is designed to act topically to minimise systemic side effects and maximize its therapeutic efficacy. Investigation of bone density in dogs with protein-losing enteropathy (PLE) We have found that dogs with severe IBD often have low vitamin D status and this has significant effects on calcium metabolism. However despite their low vitamin D status these dogs appears to rarely developing clinically significant skeletal complications unlike human counterparts with IBD where skeletal complications, including pathological fractures, are commonplace. This study aims to objectively assess bone health in dogs with intestinal disorders. This article was published on 2024-09-02
