Single Administration Vaccine Enhancement (SAVE)

Developing an implantable device that can deliver a vaccine booster into the skin.

This team is led by Heriot-Watt University. Many vaccines require boosting for optimum induction and maintenance of protective immunity. This requires multiple visits to the vet or clinician.

Here, we aim to develop a device that can be injected into the skin with the priming vaccination. This device will contain the vaccine and will be engineered so that it will burst at an appropriate time to release its contents and deliver the boost without the need for another vaccination. This project is funded by BBSRC for the period 2018-2021.

Team members: Lindsey Waddell

Team partners: Ferry Melchels (PI), Vicky Stone, Kerr Samson and Veronica Hidalgo-Alvarez at Heriot-Watt University

Key references:

Melchels, F. P., Fehr, I., Reitz, A. S., Dunker, U., Beagley, K. W., Dargaville, T. R., & Hutmacher, D. W. (2015). Initial design and physical characterization of a polymeric device for osmosis-driven delayed burst delivery of vaccines. Biotech. Bioeng. 112(9), 1927–1935. https://doi.org/10.1002/bit.25593

https://doi.org/10.21820/23987073.2018.7.6

 

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