Projects

Active Projects:

Does hormone deprivation dysregulate osteocyte function, and is this a driver of bone metastasis?  Fraser, J. (Principal Investigator), Breast Cancer Now and Prostate Cancer Research. Bone Metastasis Collaboration Fund and grant call. 2025 - 2026. £15,450. 

Improving layer hen welfare with better bone health. Dunn, I (Principal Investigator). Foundation for Food & Agriculture Research (FFAR). $2,989,012. 2023 -2028.  Project: Research

 Assessing the impact of androgen deprivation on osteocyte function. Fraser, J. (Principal Investigator), Bergkvist, G. (Co-investigator) & Farquharson, C. (Co-investigator). Society for Endocrinology. 1/03/25 → 31/12/25. Project: Research

ISP 2023/28 Consumables - Functional Genetics. Whitelaw, B. (Principal Investigator), Burdon, T. (Co-investigator), Davey, M. (Co-investigator), Farquharson, C. (Co-investigator), Headon, D. (Co-investigator), Lawrence, A. (Co-investigator), MacRae, V. (Co-investigator) & Meddle, S. (Co-investigator). Biotechnology and Biological Sciences Research Council. 1/04/23 → 31/03/28. Project: Research

Effects of gastrin receptor antagonists and proton pump inhibitors on osteoblast function and bone quality. Farquharson, C. (Principal Investigator). Trio Medicines Limited. 4/01/23 → 30/06/26. Project: Research

The Networks Influencing Osteoclast Dysregulation Leading to Bone Invasion in Cancer. Bergkvist, G. (Principal Investigator), Farquharson, C. (Co-investigator), Pang, L. (Co-investigator) & Tanveer, Q. (Student). 1/01/22 → 1/01/26. Project: Research

Completed Projects:

Humanin, a novel target to improve bone health in chronic inflammation. Farquharson, C. (Principal Investigator). European Society for Paediatric Endocrinology. 1/01/22 → 31/12/23. Project: Research

Humanin, a novel target to improve bone health in chronic inflammation. Farquharson, C. (Principal Investigator). 1/01/22 → 31/12/23. Project: Research

IDG 2021 - 23 - Capability-Small Project Grants. Whitelaw, B. (Principal Investigator), Baillie, K. (Co-investigator), Balic, A. (Co-investigator), Burdon, T. (Co-investigator), Davey, M. (Co-investigator), Farquharson, C. (Co-investigator), Fitzgerald, R. (Co-investigator), Gally, D. (Co-investigator), MacRae, V. (Co-investigator), Macqueen, D. (Co-investigator), Meddle, S. (Co-investigator), Morrison, L. (Co-investigator), Rainger, J. (Co-investigator), Tait-Burkard, C. (Co-investigator), Thekkedath Kurian, D. (Co-investigator) & Vervelde, L. (Co-investigator). Biotechnology and Biological Sciences Research Council. 6/09/21 → 31/03/24. Project: Research

Does anti-RANKL therapy prevent glucocorticoid induced bone loss and promote muscle function in a mouse model of Duchenne muscular dystrophy. Farquharson, C. (Principal Investigator). UK-based charities. 1/07/21 → 30/06/22. Project: Research

Does anti-RANKL therapy prevent glucocorticoid induced bone loss and promote muscle function in a mouse model of Duchenne muscular dystrophy. Farquharson, C. (Principal Investigator). Lifearc. 1/07/21 → 30/06/22. Project: Research

Does anti-RANKL therapy prevent glucocorticoid induced bone loss in a mouse model of Duchenne muscular dystrophy? Farquharson, C. (Principal Investigator). Duchenne Parent Project Netherlands. 1/10/20 → 31/07/22. Project: Research

Does anti-RANKL therapy prevent glucocorticoid induced bone loss in a mouse model of Duchenne muscular dystrophy? Farquharson, C. (Principal Investigator). Other. 1/10/20 → 30/04/22. Project: Research

A tale of two phosphatases: how do matrix vesicles generate phosphate for bone mineralisation. Farquharson, C. (Principal Investigator). UK-based charities. 6/05/19 → 2/01/21. Project: Research

ISP18 ECA: A tale of two phosphatases: How to matrix vesicles generate phosphate for bone mineralisation? Farquharson, C. (Principal Investigator). Biotechnology and Biological Sciences Research Council. 1/01/19 → 31/01/20. Project: Research

Potential of humanin to prevent bone growth impairment and osteoporosis in inflammatory bowel disease. Farquharson, C. (Principal Investigator). 1/10/18 → 30/09/19. Project: Research

The role of VBP6, a steroid analogue, on growth and bone health in a novel mouse model of Duchenne muscular dystrophy. Wood, C. (Principal Investigator) & Farquharson, C. (Co-investigator). UK-based charities. 1/01/18 → 31/12/18. Project: Research

ISP 2017/22-Farquharson Colin. Farquharson, C. (Principal Investigator). Biotechnology and Biological Sciences Research Council. 1/04/17 → 31/03/23. Project: Research

ISP 2017/22-Farquharson Colin. Farquharson, C. (Principal Investigator). Biotechnology and Biological Sciences Research Council. 1/04/17 → 31/03/22. Project: Research

Are the catabolic skeletal effects of continuous in vivo PTH administration in the mouse mediated by PHOSPHO1 expression? Farquharson, C. (Principal Investigator). UK-based charities. 31/05/16 → 9/08/16. Project: Research

Does deregulated PHOSPHO1 expression contribute to catabolic bone loss in hyperparathyroid hormone disorders? Farquharson, C. (Principal Investigator). UK-based charities. 30/05/16 → 22/07/16. Project: Research

NEWTON-Bhabha PhD placements - Mojeer Hasan. Farquharson, C. (Principal Investigator). UK central government bodies/local authorities, health and hospital authorities. 1/05/16 → 31/10/16. Project: Research

Development of assays to assess the clinical utility of tenascin-C in inflammatory diseases. Farquharson, C. (Principal Investigator). UK industry, commerce, and public corporations. 1/10/15 → 30/09/19. Project: Research

Development of assays to assess the clinical utility of tenascin-C in inflammatory diseases. Farquharson, C. (Principal Investigator). UK-based charities. 1/10/15 → 30/09/19. Project: Research

Is the protection from obesity and diabetes observed in the Phosphol1 KO mouse driven by bone? Farquharson, C. (Principal Investigator). Biotechnology and Biological Sciences Research Council. 1/05/14 → 31/07/15. Project: Research

Subchondral bone sclerosis in OA is driven by defective mineralisation and osteocyte formation. Farquharson, C. (Principal Investigator). UK-based charities. 1/01/14 → 31/12/16. Project: Research

Eastbio Doctoral Training Partnership. Farquharson, C. (Principal Investigator) & MacRae, V. (Co-investigator). Biotechnology and Biological Sciences Research Council. 1/10/12 → 30/09/18. Project: Research

Determination of whole-body composition of phospho1 null mice by magnetic resonance imaging. Farquharson, C. (Principal Investigator). Biotechnology and Biological Sciences Research Council. 1/09/12 → 31/03/13. Project: Research

Control of development and reproductive traits. Burdon, T. (Principal Investigator), Argyle, D. (Co-investigator), Ashworth, C. (Co-investigator), Beard, P. (Co-investigator), Brunton, P. (Co-investigator), Burt, D. (Co-investigator), Clinton, M. (Co-investigator), Dunn, I. (Co-investigator), Farquharson, C. (Co-investigator), Headon, D. (Co-investigator), Hocking, P. (Co-investigator), Hohenstein, P. (Co-investigator), Hume, D. (Co-investigator), Jackson, I. (Co-investigator), McColl, B. (Co-investigator), McGrew, M. (Co-investigator), McLachlan, G. (Co-investigator), Sang, H. (Co-investigator), Summers, K. (Co-investigator) & Whitelaw, B. (Co-investigator). Biotechnology and Biological Sciences Research Council. 1/04/12 → 31/03/17. Project: Research

A yeast two-hybrid screen to identify substrate/binding proteins to PHOSPHO1. Farquharson, C. (Principal Investigator). Biotechnology and Biological Sciences Research Council. 1/10/10 → 31/03/12. Project: Research

Unravelling the SOCS2 molecular mechanisms that underpin bone growth and development-Studentship Ross Dobie. Farquharson, C. (Principal Investigator) & MacRae, V. (Co-investigator). UK industry, commerce, and public corporations. 14/09/10 → 13/09/14. Project: Research

Csf1 and the control of postnatal growth and organ development in the rat. Hume, D. (Principal Investigator), Burdon, T. (Co-investigator), Farquharson, C. (Co-investigator) & Whitelaw, B. (Co-investigator). MRC. 12/07/10 → 11/06/14. Project: Research

Support grant to R82602. Farquharson, C. (Principal Investigator). Biotechnology and Biological Sciences Research Council. 1/05/10 → 30/09/13. Project: Research

The effects of chronic inflammatory disease on growth and skeletal development in the SOCS2-deficient mouse. Farquharson, C. (Principal Investigator). UK-based charities. 1/12/09 → 31/12/14. Project: Research

Bench Fees Abertay MSc - Rhadakrishna Patulla. Farquharson, C. (Principal Investigator). 1/08/09 → 30/07/10. Project: Research

Unravelling the regulatory mechanisms controlling inorganic phosphate (pi) mobilisation during growth plate mineralisation and bone development. Studentship Katherine Staines. Farquharson, C. (Principal Investigator). Biotechnology and Biological Sciences Research Council. 15/09/08 → 14/09/12. Project: Research

Signalling in bone growth and development: DTG Studentship P Newton. Farquharson, C. (Principal Investigator). Biotechnology and Biological Sciences Research Council. 1/05/08 → 31/03/11. Project: Research

Mechanisms of initiation of skeletal mineralisation. Farquharson, C. (Principal Investigator). EU government bodies. 1/05/08 → 10/11/11. Project: Research

Role of SOCS2 in the growth retardation of chronic inflammatory disease. Farquharson, C. (Principal Investigator) & MacRae, V. (Co-investigator). Biotechnology and Biological Sciences Research Council. 1/05/08 → 30/09/10. Project: Research