Division of Bacteriology

Research in the Bacteriology Division aims to meet the challenges of sustainable agriculture, enhancing the health of humans and animals, and infectious diseases - with particular focus on key endemic livestock and zoonotic diseases.

Sustainable Agriculture 

Our research activities impact key endemic livestock and zoonotic diseases, creating an inseparable link to sustainable agriculture practices.  .  

Infectious Diseases 

We employ an array of genomic approaches including phylodynamics, transposon mutagenesis and hybrid applications such as TraDIS, and machine learning to explore disease transmission, and the key genes and pathways associated with colonisation, pathogenesis and host-tropism. 

We also use a variety of functional, metabolic and infection assays including cellular and organoid systems to dissect the molecular pathogenesis of bacterial diseases. 

We are addressing the global challenge of antimicrobial resistance developing and test new approaches for controlling infections including vaccines, sequence-based diagnostics informing appropriate antibiotic treatment and alternatives to antibiotics such as phage therapy

Enhancing Health 

We are working in partnership with various stakeholders including public health bodies, animal breeding and pharmaceutical companies to translate our findings into improved animal and public health, and improved food security.

The laboratory is focused on the evolution and pathogenesis of clinically important species of Staphylococci including the major human and animal pathogen Staphylococcus aureus.

The overall interest of the Lynskey Lab is the study of virulence factor regulation and innate immune modulation by pathogenic streptococci.