Cell Lines

Cell Lines

Reagent Cat. No. Description
SMB.s15 RC 040 Scrapie(Chandler) Mouse Brain cells, cloned
SMB-PS RC 041 SMB.s15 cured with Pentosan polysulphate
SMB[22F].F4 RC 045 SMB-PS infected with murine passaged scrapie, strain 22F

Culture information - for all the above cell lines.

References

for SMB.s15 and derivative cells: Birkett CR, Hennion RM, Bembridge DA, Clarke MC, Chree A, Bruce ME, Bostock CJ "Scrapie strains maintain biological phenotypes on propagation in a cell line in culture" The EMBO Journal, Vol. 20, No. 13 pp. 3351-3358, 2001.

for original SMB cells: Clarke MC, Haig DA; Nature 1970 Jan 3; 225 (5227) 100-101. Evidence for the multiplication of scrapie agent in cell culture. (Letter) Clarke MC, Haig DA; Research in Veterinary Science 1970 Sep; 11 (5) 500-501. Multiplication of scrapie agent in cell culture. Clarke MC, Millson GC; Journal of General Virology 1976 June; 31 (3) 441-445. The membrane location of scrapie infectivity.