LARIF provides a dedicated large-animal cardiovascular research facility for translational research and preclinical studies in pigs, sheep, cattle and horses. LARIF combines CT, MRI, echocardiography, fluoroscopy and electrophysiology within a single facility which allows researchers to investigate cardiovascular structure, function and disease using clinically relevant imaging and interventional technologies. Studies which can be supported by the facilities offered by LARIF include:assessment of cardiac structure, function and perfusiondevelopment and validation of cardiovascular imaging techniqueselectrophysiology and cardiac mapping researchevaluation of novel cardiovascular devices and therapiesimage-guided cardiovascular interventions.Core capabilitiesComputed Tomography (CT)Siemens SOMATOM Xceed128 slice scannerECG-gated cardiac imagingmultiphase contrast administrationhigh-resolution anatomical and vascular imaging.Magnetic Resonance Imaging (MRI)Siemens 3 Tesla (3T)ECG-gated cardiac imagingcontrast-enhanced studiesassessment of cardiac structure, function and tissue characterisationvascular and perfusion imaging.Echocardiographytwo- and three-dimensional imagingnon-invasive assessment of cardiac anatomy and functionsupports longitudinal cardiovascular studies.Fluoroscopyreal-time image guidancesupport for cardiovascular interventions and device studies.Electrophysiology laboratory80-channel Boston Scientific electrophysiology recording systemAbbott Precision™ 3D electroanatomic mappingadvanced cardiac mapping and rhythm researchsuitable for studies ranging from sheep to horses. This article was published on Friday 21 August 2026