Publications

Most recent publications from the Rainger lab:

Preprint: 

The regulatory landscape of optic fissure closure in the vertebrate eye.

Brian Ho Ching Chan, Mariya Moosajee, Holly Hardy, James Prendergast, Joe Rainger

bioRxiv 2026.02.11.705341; doi: https://doi.org/10.64898/2026.02.11.705341

Preprint: 

FuChi: A cell cycle biosensor for investigating cell-cycle kinetics during avian development.

Zoe R. Sudderick, Tiernan Briggs, Shirooza Mubarak, Melinda Van Kerckvoorde, Ana R. Hernandez-Rodriguez, Sudeepta K. Panda, Jon Riddell;, Cameron Batho-Samblas, Lorna Taylor, Lynn McTeir, Dominique Meunier, Amy Findlay, Flossie Roberts, Anna Raper, Asako Sakaue-Sawano, Atsushi Miyawaki, Joe Rainger, Jeffrey J. Schoenebeck, Cornelis J. Weijer, Mike J. McGrew, Denis J. Headon, Megan G. Davey, Richard L. Mort, James D. Glover

bioRxiv 2025.09.24.678103; doi: https://doi.org/10.1101/2025.09.24.678103

Published Research Outputs from the Rainger Lab:

  1. Variant-specific disruption to notch signalling in PAX6 microphthalmia and aniridia patient-derived hiPSC optic cup-like organoids. Harding, P., Nicholas, O., Eintracht, J., Cunha, D. L., Chan, H. C. B., Rainger, J. & Moosajee, M., Aug 2025, In: BBA - Molecular Basis of Disease. 1871, 6, p. 1-38 38 p., 167869. Research output: Contribution to journal › Article › peer-review
  2. A stable NTN1 fluorescent reporter chicken reveals cell specific molecular signatures during optic fissure closure. Chan, H. C. B., Hardy, H., Requena Navarro, T., Findlay, A., Ioannidis, J., Meunier, D., Toms, M., Moosajee, M., Raper, A., McGrew, M. & Rainger, J., 24 Mar 2025, In: Scientific Reports. 15, 1, p. 1-12 12 p., 10096. Research output: Contribution to journal › Article › peer-review
  3. Cell adhesion marker expression dynamics during fusion of the optic fissure. Hardy, H. & Rainger, J., Dec 2023, In: Gene Expression Patterns. 50, p. 1-8 8 p., 119344. Research output: Contribution to journal › Article › peer-review
  4. Identification of novel coloboma candidate genes through conserved gene expression analyses across four vertebrate species. Trejo-Reveles, V., Nicholas, O., Chan, H. C. B., Toms, M., Schoenebeck, J., Moosajee, M. & Rainger, J., 4 Feb 2023, In: Biomolecules. 13, 2, p. 1-18 17 p., 293. Research output: Contribution to journal › Article › peer-review
  5. Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia. Hall, H. N., Bengani, H., Hufnagel, R. B., Damante, G., Ansari, M., Marsh, J. A., Grimes, G. R., Kriegsheim, A. V., Moore, D., McKie, L., Rahmat, J., Mio, C., Blyth, M., Keng, W. T., Islam, L., McEntargart, M., Mannens, M. M., Heyningen, V. V., Rainger, J. & Brooks, B. P. & 1 others, , Nov 2022, In: PLoS ONE. 17, 11, p. 1-21 20 p., e0268149. Research output: Contribution to journal › Article › peer-review
  6. Robust genetic analysis of the X-linked anophthalmic (Ie) mouse. Hernandez Moran, B. A., Papanastasiou, A. S., Parry, D., Meynert, A. M., Gautier, P., Grimes, G., Adams, I. R., Trejo-Reveles, V., Bengani, H., Keighren, M., Jackson, I. J., Adams, D. J., FitzPatrick, D. R. & Rainger, J., 5 Oct 2022, In: Genes. 13, 10, p. 1-14 14 p., 1797.Research output: Contribution to journal › Article › peer-review

All Rainger lab research publication outputs can be viewed on the University of Edinburgh Research Profile here: 

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