This workshop gives a real insight and practical hands-on experience on what life in the lab is like here at The Roslin Institute through the science of Christine Tait-Burkard and her success in creating disease resistant pigs. This hands-on CLPL workshop, for secondary school science teachers, will be a technique refresher focused on gel electrophoresis. Learning Level: Secondary Biology TeachersLocation: Charnock Bradley Building Reception, 10 minutes before the workshop start timeAvailability: On demand Cost: £300 per workshop, maximum attendance is 20 peopleDuration: 4 hours (with 30 minutes for lunch) + tour of The Roslin InstituteBooking: please email ebsoc@ed.ac.uk for booking enquiries in 2024Join the Easter Bush Science Outreach Centre (EBSOC) team to get a unique chance to do our Real-Life Roslin Research: Which Little Piggy? workshop. You will be introduced to the current, cutting-edge research of Dr Christine Tait-Burkard and her team who have used genome-editing technology to engineer pigs that are genetically resistant to an infectious disease called porcine reproductive and respiratory syndrome (PRRS). The workshop will reveal how they use molecular biology techniques to genotype engineered pigs. Learning ObjectivesTo understand how scientific research is used to solve global animal health and welfare problemsTo develop scientific thinking and critical analysis skillsTo understand how gene editing works and can be used in the labTo understand that we can identify genotypes using DNA profilingTo interpret and discuss experimental resultsTo reveal the world of work in scientific researchTechniques UsedMicro-pipettingDNA gel electrophoresisWorkshop outlineIntroduction to gene editingIntroduction to micropipettesPreparation of DNA for fragment analysisDNA electrophoresis using agarose gelsAnalysis and interpretation of resultsEthical discussion about use of genome edited animals in farmingGetting here:Free parking is available at Easter Bush Campus in The Roslin Institute and Veterinary Teaching Building car parks. Please provide your car registration at Charnock Bradley Building reception when you check in for the event.The campus is well-served by Lothian buses (buses 15, some 37 services, the X47 (but not the 47) and the 67) – please see www.lothianbuses.com. For more information please download our How to Get Here document Accessibility and Inclusion:We are keen to make our events as inclusive as possible - please email us at ebsoc@ed.ac.uk or call the Easter Bush Science Outreach Centre team on 0131 651 9679 before booking if you would like to find out more about accessibility or usability.To remain updated about all our workshops, events and exciting opportunites please join our mailing list by clicking here or follow us on Twitter @EBSOClab. Risk Assessment: Document Insight into Roslin Research- Which Little Piggy? Risk Assessment (825.13 KB / PDF) Read more about the science behind the workshop:Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function Burkard, C, Lillico, S, Reid, E, Jackson, B, Mileham, AJ, Ait-Ali, T, Whitelaw, C & Archibald, A 2017 Genome Editing for Disease Resistance in Livestock Proudfoot, C & Tait-Burkard, C 2017 This article was published on 2024-09-02